Question 1

What is the new recommendation for TEER in secondary mitral regurgitation?

Accepted Answer

TEER is now a Class I recommendation for highly selected patients with ventricular secondary MR who remain symptomatic despite optimal guideline-directed medical therapy.

Question 2

How has the management of primary mitral regurgitation changed?

Accepted Answer

While surgery remains the gold standard, there is a new Class I recommendation for intervening in asymptomatic patients based on indexed left ventricular end-systolic dimensions.

Question 3

What are the major updates for treating tricuspid regurgitation?

Accepted Answer

The guidelines emphasize early referral and upgrade transcatheter interventions to Class IIa for high-risk symptomatic patients, provided they lack severe right ventricular dysfunction or precapillary pulmonary hypertension.

New 2025 ESC/EACTS Guidelines: How Should We Manage Mitral and Tricuspid Regurgitation?